On Wednesday both D.C. and Maryland recorded the largest number of new daily COVID-19 cases the jurisdictions have seen since May. The numbers come amid an overall spike in coronavirus cases across the region and a worsening national caseload.

The District tallied 206 infections on Wednesday. That’s a huge jump from the 86 new cases reported on Tuesday, though caseloads have been climbing since the end of September.

The last time D.C. saw more than 200 new daily COVID-19 cases was May 21, according to official data tracked by DCist/WAMU (the next-closest high was 179 cases on May 30). The District had occasionally recorded more than 100 new daily COVID-19 infections since late October.

No new coronavirus-related deaths were reported, D.C. Mayor Muriel Bowser’s office said in a release. The District’s total positive caseload is now 18,379.

Maryland also recorded a major spike in new COVID-19 cases on Wednesday: 1,714. The last time it saw so many new infections was on May 19, but it has now recorded high caseloads of 1,000 or more for eight days straight. Maryland has 158,423 confirmed cases in total.

On Tuesday, the Maryland Department of Health activated plans for hospital surge capacity in light of the surge in cases, and Gov. Larry Hogan also announced tightened restaurant restrictions and urged counties to enforce pandemic rules.

Virginia saw 1,594 new infections on Wednesday, for a total of 196,506 COVID-19 cases recorded during the pandemic. Cases recently spiked on Nov. 7, when the commonwealth reported 2,103 new coronavirus infections, and they’ve been trending up since early October.

Area public health officials recently warned that the region is at a turning point in the pandemic, and say if cases continue to spike unchecked, the local health care system could be completely overwhelmed. While it’s difficult to determine the exact cause of the surge, general fatigue with COVID-19 guidelines like social distancing and wearing a mask is likely leading to riskier behavior.