The annual March For Life – the nation’s largest anti-abortion rally – is happening Friday, marking 50 years since organizers started marching in 1974.

It’s the second march since the Supreme Court overturned Roe v. Wade in June 2022, and organizers are expecting around 50,000 attendees, according to the National Park Service permit issued for the march. The march will start at around 1 p.m. between 12th and 14th Streets and will proceed along Constitution Avenue to the U.S. Capitol Building, following a rally at noon and pre-rally concert at 11 a.m.

In 2023, marchers took on a slightly different route from previous years to “maintain a presence” in Washington and to mark the passage of Dobbs v. Jackson, which ended the constitutional right to abortion. This year, they’ll be taking the same route they took last year, marching past the Capitol and finishing between the Capitol and Supreme Court buildings. Organizers say that “even with the wonderful blessing of Roe v. Wade being overturned,” they’re still marching to fulfill their goal of making abortion “unthinkable.”

There’ll be road closures as usual. From 10 a.m. to 4 p.m. on Friday, the following streets will be off limits to vehicles:

• Constitution Avenue from 15th Street to 3rd Street, NW
• Pennsylvania Avenue from 7th Street, NW to 3rd Street, NW
• 12th Street from Pennsylvania Avenue to Madison Drive, NW
• 12th Street Tunnel
• 10th Street from Pennsylvania Avenue to Constitution Avenue, NW
• 9th Street from Pennsylvania Avenue to Constitution Avenue, NW
• 9th Street Tunnel
• 7th Street from Pennsylvania Avenue, NW to Independence Avenue, SW
• 6th Street from Pennsylvania Avenue to Constitution Avenue, NW
• 4th Street from Pennsylvania Avenue, NW to Independence Avenue, SW
• 3rd Street from Indiana Avenue, NW to Independence Avenue, SW
• Madison Drive from 14th Street to 7th Street, NW
• Jefferson Drive from 14th Street to 7th Street, SW

In addition, 14th Street from Pennsylvania Avenue, NW to Independence Avenue, SW may be closed to traffic.

From 6 a.m. to 4 p.m., drivers may not park in the following streets:

• Constitution Avenue from 15th Street to 3rd Street, NW
• Pennsylvania Avenue from 7th Street to 3rd Street, NW
• 14th Street from Pennsylvania Avenue, NW to Independence Avenue, SW
• 12th Street from Pennsylvania Avenue to Madison Drive, NW
• 10th Street from Pennsylvania Avenue to Constitution Avenue, NW
• 9th Street from Pennsylvania Avenue to Constitution Avenue, NW
• 7th Street from Pennsylvania Avenue, NW to Independence Avenue, SW
• 6th Street from Pennsylvania Avenue to Constitution Avenue, NW
• 4th Street from Pennsylvania Avenue, NW to Independence Avenue, SW
• 3rd Street from Indiana Avenue, NW to Independence Avenue, SW
• Madison Drive from 14th Street to 7th Street, NW
• Jefferson Drive from 14th Street to 7th Street, SW

Road closures are subject to change.

The National Women’s March is usually held in D.C. around this time, and in the past it has drawn tens of thousands of supporters. This year, however, the main Women’s March will be held in Phoenix, AZ on Saturday. There’ll be a smaller march in D.C. that day at Freedom Plaza on 15th St NW, starting at around 11. The permit request was for around 500 attendees — a significantly smaller rally than in past years — according to the National Park Service.